Functionalised liposomal formulations for delivery of antibiotic agents
نویسندگان
چکیده
منابع مشابه
Liposomal Delivery of Antileishmanial Agents
Initially, the use of liposomes was mainly confined to model membrane systems, however, recently their use as vehicles for transfer of genetic and other materials into cells in cultures or for drug delivery to desired cellular and subcellular sites in a living system has been the subject of discussion. Liposomes can vary widely in size, chemical composition, and surface characteristics; they ca...
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Photodynamic therapy is a clinically approved treatment for cancer and noncancer diseases. This modality utilises light-activatable chemicals (photosensitising agents) to capture photons and use light energy for the production of cytotoxic reactive molecular species. Most photosensitisers that are in use clinically or in preclinical development are hydrophobic and tend to aggregate in the aqueo...
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Although widely used in chemotherapy, free doxorubicin (Dox) might enhance cell malignancy undesirably. Liposomal Dox (Doxlipo) has been clinically approved for the treatment of breast cancer due to reduced systematical toxicity and increased tumor targeting, yet the transcriptome-wide elucidation of the Doxlipo formulations remains elusive. To this end, we explored the impact of two Dox liposo...
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Liposomes, basically including lecithin and cholesterol, are classic nanovesicles to treat some diseases clinically. As the first FDA approved nanomedicine, Doxil® (Doxorubicin HCl Liposome Injection) is a successful formulation to inhibit the development of some cancer and improve the life time of the patients after tumor surgery [1]. However, the non-specific accumulation of liposomes in Reti...
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Colon targeted drug delivery is an active area of research for diseases affecting the colon, as it shows promise in improving the efficacy of therapeutics and reducing systemic toxicity. Improved oral drug delivery design has unequivocally improved the bioavailability of drugs to the colon. The oral route of administration is the most common method of drug delivery. It is the preferred route of...
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ژورنال
عنوان ژورنال: Access Microbiology
سال: 2019
ISSN: 2516-8290
DOI: 10.1099/acmi.ac2019.po0507